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Artificial fragrance free

Dye free

Paraben free

Sulfate free

Phthalate free

Animal cruelty free

IntelliRET™ 0.5+

IntelliRET™ 0.5+

$145.00
$145.00
Sale Sold out
30 mL / 1 fl oz
Suits:
Resilient Skin Types
Targets:
Blemish-Prone Ageing Discolouration Redness-Prone / Sensitive

An advanced-strength retinol serum powered by intelligent time-release technology and a bio-inspired botanical complex that boosts the effects of retinol, targeting deeper lines, loss of firmness, and uneven tone for a smoother, more radiant complexion with optimal skin tolerance.

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Description

An advanced-strength retinol serum powered by intelligent time-release technology and a bio-inspired botanical complex that boosts the effects of retinol, targeting deeper lines, loss of firmness, and uneven tone for a smoother, more radiant complexion with optimal skin tolerance.

IntelliRET™ 0.5+ is a high-performance retinol serum for established retinol users ready to step up their results. With 0.5% retinol, it targets deeper fine lines and wrinkles, loss of firmness, blemishes, uneven tone, and texture. The same innovative bio-inspired botanical complex found in IntelliRET™ 0.3+ enhances the efficacy of retinol and improves skin tolerance, helping you progress your retinol routine without the disruption traditionally associated with higher strengths.

At the core of its delivery system is cutting-edge microencapsulated retinol, which allows for a gradual, timed-release overnight, maximizing efficacy while minimizing irritation. The formula is further enriched with soothing and hydrating ingredients like niacinamide and sodium hyaluronate for visible results, delivered in comfort.

IntelliRET™ 0.5+ is part of AlumierMD’s Core 4 Essentials, designed to target visible signs of aging driven by Oxidative Aging™ and support long-term skin resilience as part of a complete daily defense approach.

Contains Vitamin A. Consider your daily intake before use.

Key Benefits
  • Higher-strength retinol performance that targets the appearance of deeper fine lines, loss of firmness, uneven tone, and skin texture irregularities with greater intensity than 0.3+.
  • Bio-inspired botanical booster (Chlorella vulgaris) amplifies visible results and supports a more balanced skin response at higher retinol concentration.
  • Microencapsulated retinol for controlled, gradual delivery, maintaining performance gains while reducing the barrier disruption typically associated with stronger retinol.
  • Niacinamide reinforces barrier integrity and supports moisture retention for comfortable, consistent use.
  • MATRIXYL® Synthe'6® visibly supports skin structure and firmness, complementing retinol's smoothing effects.
  • Helps reduce the appearance of uneven tone and dark spots with continued use.
  • Part of the IntelliRET™ progressive strength pathway: step two between 0.3+ and 1.0+.
  • Precision-dose needlenose tube for controlled, hygienic application. For use under professional guidance.

Directions

Apply a pea sized amount to face after cleansing at night. Follow with your favorite AlumierMD moisturizer. Recommended once your skin is comfortable with nightly use of IntelliRET™ 0.3+ or another retinol. Begin using two to three times a week and gradually increase frequency to nightly as your skin adjusts, as directed by your skincare professional. Not recommended for rosacea or highly reactive skin.

Cautions: For external use only. Avoid contact with eyes, eyelids, and mucous membranes. Keep out of reach of children. Use only as directed. If irritation occurs or persists, discontinue use and consult a physician. Do not use if you are pregnant, lactating or planning to become pregnant.

Contains Vitamin A. Consider your daily intake before use.

Sunburn Alert: This product contains retinol that may increase your skin's sensitivity to the sun and particularly the possibility of sunburn. Use sunscreen, wear protective clothing, and limit sun exposure while using this product and for a week afterwards.


Ingredients

Microencapsulated Retinol (0.5%): A vitamin A derivative and antioxidant that reduces the look of fine lines and wrinkles and improves texture and tone by strengthening skin, and increasing skin turnover. Retinol exfoliates to help decongest pores and reduce the look of discoloration, making it suitable for blemish-prone skin. Encapsulated retinol allows for a slow release into the skin overnight minimizing side effects, so you can enjoy all the benefits of retinol with little to no irritation.

Niacinamide (vitamin B3): Along with keeping in moisture and boosting hydration, it also increases tolerance to topical retinoids.

MATRIXYL® Synthe'6®: Derived from a peptide naturally found in collagen and laminins, this visibly supports skin structure and targets the look of stubborn wrinkles and skin firmness.

Tetrapeptide-14, Green Tea Extract, Boswellia Serrata Gum: A peptide combined with the antioxidant properties of green tea and the soothing qualities of boswellia.

Sodium Hyaluronate: A salt form of hyaluronic acid that hydrates by drawing water into the outer layers from within the skin. It holds up to 1,000 times its weight in water, making skin appear plumper, softer and smoother.

Full Ingredient List: WATER/AQUA/EAU, GLYCERIN, PROPANEDIOL, DIMETHICONE, CAPRYLIC/CAPRIC TRIGLYCERIDE, ISOSTEARYL ALCOHOL, HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER, NIACINAMIDE, RETINOL, BOSWELLIA SERRATA GUM, CAMELLIA SINENSIS LEAF EXTRACT, ALOE BARBADENSIS LEAF JUICE, CHLORELLA VULGARIS EXTRACT, TETRAPEPTIDE-14, PALMITOYL TRIPEPTIDE-38, HYDROXYPROPYL CYCLODEXTRIN, SODIUM HYALURONATE, HYDROLYZED HYALURONIC ACID, LECITHIN, AMMONIUM ACRYLOYLDIMETHYLTAURATE/VP COPOLYMER, GLUCONOLACTONE, POLYSILICONE-11, POLYURETHANE CROSSPOLYMER-1, BUTYLENE GLYCOL, XANTHAN GUM, TOCOPHEROL, SORBITAN ISOSTEARATE, METHYLPROPANEDIOL, POLYVINYL ALCOHOL, CAPRYLYL GLYCOL, CALCIUM GLUCONATE, HYDROXYACETOPHENONE, DECYL GLUCOSIDE, PHENYLPROPANOL, LACTIC ACID, CITRIC ACID, DISODIUM EDTA, SODIUM HYDROXIDE, SODIUM BENZOATE, 1,2-HEXANEDIOL.

Backed by Science

Achieving stronger retinol results has traditionally meant accepting greater skin disruption. This trade-off exists because higher retinol concentrations increase the rate and intensity of skin cell turnover, but without adequate barrier support this acceleration can outpace the skin's ability to maintain comfort and integrity.

IntelliRET™ 0.5+ is engineered to decouple retinol strength from retinol disruption. The microencapsulation system controls the delivery rate of retinol at 0.5% concentration, reducing the irritation peak without reducing efficacy. The bio-inspired botanical booster (Chlorella vulgaris) works in synergy to amplify the visible renewal response while actively supporting a more balanced skin reaction, helping the skin better adapt to the higher concentration over time.

At this strength, users can expect more visible improvements in fine lines, skin texture, firmness, and uneven tone compared to 0.3+. The supporting ingredient system of Niacinamide, Matrixyl® Synthe'6™, the calming complex, and Sodium Hyaluronate is designed to maintain the barrier and comfort conditions needed to sustain those results over the long term. This is advanced retinol performance, made sustainable.

Artificial fragrance free

Dye free

Paraben free

Sulfate free

Phthalate free

Animal cruelty free
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Complete your routine

Retinol. Reengineered.

IntelliRET™ 0.5+ retinol serum

Retinol. Reengineered.

IntelliRET™ is a core pillar of the AlumierMD CORE 4 Essentials, a clinically grounded retinol system built for the realities of modern skin. Every IntelliRET™ formula is developed by a global team of scientists and medical professionals with over 100 years of combined industry experience, validated through independent clinical trials, and available exclusively through AlumierMD-authorized clinics and professionals in 12+ countries. Speak to your AlumierMD professional to find out which IntelliRET™ strength is right for your skin.

Questions, answered

Still unsure what fits your routine?

Ask your AlumierMD skincare professional

What is the best vitamin C serum for anti-aging and skin brightening?

For maximum antioxidant efficacy and anti-aging benefit, AlumierMD’s EverActive C&E® + Peptide is the gold standard in our collection. It delivers 15% L-Ascorbic Acid USP, the only form of vitamin C with full clinical substantiation, in a unique freshness-preserving delivery system that keeps the active ingredient stable until the moment of use. This prevents the oxidation that renders most vitamin C serums ineffective, ensuring consistent, clinical-level performance. Applied in the morning, it provides the antioxidant defence required to neutralize the free radicals that drive Oxidative Aging™.

How do I layer different AlumierMD serums effectively?

Layering is a core component of a professionally prescribed AlumierMD regimen. As a general principle, thinner, water-based formulations are applied first, allowing them to penetrate before richer, emollient serums seal in their actives. However, the precise layering order, timing, and which serums to combine will depend on your specific skin concerns and sensitivities. A certified AlumierMD professional will build this sequence into your customized regimen to maximize efficacy and tolerability.

Can I use a retinol serum every day?

The appropriate frequency for retinol use is highly individual and depends on the strength prescribed, your skin’s baseline tolerance, and your treatment goals. AlumierMD’s tiered retinol range, progressing from 0.25 to 0.5 and 1.0, allows for a controlled, professionally guided introduction that builds tolerance over time. Our microencapsulated retinol formulations release the active gradually, reducing the risk of irritation while maintaining efficacy.

How do AlumierMD serums protect against Oxidative Aging™?

Oxidative Aging™ is the process by which free radicals generated by UV, pollution, and infrared exposure damage the skin’s structural proteins and trigger visible premature aging. AlumierMD serums address this through multiple mechanisms: antioxidants in EverActive C&E® + Peptide neutralize surface-level free radicals; Alumience A.G.E.® targets the glycation pathway that stiffens structural fibres; and retinol stimulates cellular renewal to replace damaged cells with healthier ones.

How do I order AlumierMD products?

To order AlumierMD products, you must link your account to one of our certified clinics during checkout. A prior consultation is not required, but we recommend one to ensure your antioxidant strategy is precisely tailored to your skin's needs and goals. Our Skincare Quiz is available for initial guidance.